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Lipid peroxidation inhibitor 1  (Synonyms: 脂质过氧化抑制剂1)

目录号: HY-U00319
产品使用指南

摩尔计算器

Lipid peroxidation inhibitor 1 是一种脂质过氧化 (lipid peroxidation) 抑制剂，其 IC50 值为 0.07 μM。

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Lipid peroxidation inhibitor 1 Chemical Structure

Lipid peroxidation inhibitor 1 Chemical Structure

CAS No. : 142873-41-4

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Lipid peroxidation inhibitor 1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lipid peroxidation inhibitor 1 is a lipid peroxidation inhibitor with an IC50 of 0.07 μM.

IC50 & Target

IC50: 0.07μM (lipid peroxidation)[1]
体外研究
(In Vitro)

Among the compounds synthesized, Lipid peroxidation inhibitor 1 (26n) exhibits potent effects in the inhibition of lipid peroxidation, with an IC50 of 0.07 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lipid peroxidation inhibitor 1 相关抗体:
体内研究
(In Vivo)

Basic molecules 8a and 27 exhibit significant effects against (methamphetamine) MAP-induced hypermotility. Except in these compounds, a phenyl group adjacent to the methyl group in position 2 at a distance seems to be indispensable (compare compounds 26m, o, p with compounds Lipid peroxidation inhibitor 1 (26n), q, r). Among these compounds, Lipid peroxidation inhibitor 1 which has a phenylpiperidinyl group in position 2 is found to be most effective[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

364.52

Formula

C24H32N2O
CAS 号
中文名称

脂质过氧化抑制剂1
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Cell Assay
[1]

To rat liver microsomes (S-9) (0.3 mg of protein/40 mM Tris-malate buffer (pH 7.4), 2.4 mL) (2.4 mL) is added a mixture (1:1; 0.1 mL) of aqueous FeCl2 solution (0.25 mM) and NADPH (3 mM). After incubation of the homogenate for 1 h at 37 °C, peroxide production is determined by the thiobarbituric acid method. The inhibitory activities on lipid peroxidation are expressed as IC50 values or percent inhibition as compare with the amount of production in the vehicle (DMSO) group[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Administration
[1]

Five-week old male mice (25 to 35 g) are used. Following a 90 min acclimation period, the test compounds (including Lipid peroxidation inhibitor 1) suspended in 5% gum arabic are injected intraperitoneally in a volume of 20 mL/kg. Thirty minutes after treatment with test compounds, methamphetamine dissolved in saline is injected intraperitoneally at a dose of 1 mg/kg in a volume of 20 mL/kg. Immediately after methamphetamine injection, spontaneous motor activity is monitored for 90 min[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Lipid peroxidation inhibitor 1 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lipid peroxidation inhibitor 1142873-41-4脂质过氧化抑制剂1Lipid peroxidation inhibitor1Lipid peroxidation inhibitor-1OthersInhibitorinhibitorinhibit

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